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1

Structural characterization of human heme oxygenase-1 in complex with azole-based inhibitors

Mona N. Rahman, Jason Z. Vlahakis, Gheorghe Roman, Dragic Vukomanovic, Walter A. Szarek, Kanji Nakatsu, Zongchao Jia

Journal:

Journal of Inorganic Biochemistry

Year:

2010

Language:

english

File:

PDF, 582 KB

english, 2010

2

Evaluation of 3,6-dibutanoylmorphine as an analgesic in vivo: Comparison with morphine and 3,6-diacetylmorphine

R. Andrew, R. Tasker, Kanji Nakatsu

Journal:

Year:

1984

Language:

english

File:

PDF, 398 KB

english, 1984

3

Spreadsheets, data handling and statistics

Kanji Nakatsu, James A. Owen

Journal:

Trends in Pharmacological Sciences

Year:

1989

Language:

english

File:

PDF, 548 KB

english, 1989

4

Relative cataleptic potency of narcotic analgesics, including 3,6-dibutanoylmorphine and 6-monoacetylmorphine

Tasker, Richard A.R., Vander^Velden, Peter L., Nakatsu, Kanji

Journal:

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Year:

1984

Language:

english

File:

PDF, 267 KB

english, 1984

5

Comparison of short inversion time inversion recovery (STIR) and fat-saturated (chemsat) techniques for background fat intensity suppression in cervical and thoracic MR imaging

Masashi Nakatsu, Hiroto Hatabu, Harumi Itoh, Kenji Morikawa, Yukio Miki, Kanji Kasagi, Taro Shimono, Kazuhiko Shoji, Yutaka Shimada, Masayuki Imamura, Junji Konishi

Journal:

Journal of Magnetic Resonance Imaging

Year:

2000

Language:

english

File:

PDF, 316 KB

english, 2000

6

Assay of glyceryl trinitrate, isosorbide dinitrate, and their metabolites in plasma by large-bore capillary column gas-liquid chromatography

Brian P. Booth, Brian M. Bennett, James F. Brien, Douglas A. Elliott, Gerald S. Marks, John L. McCans, Kanji Nakatsu

Journal:

Biopharmaceutics & Drug Disposition

Year:

1990

Language:

english

File:

PDF, 636 KB

english, 1990

7

Synthesis and Evaluation of Azalanstat Analogues as Heme Oxygenase Inhibitors.

Jason Z. Vlahakis, Robert T. Kinobe, Raymond J. Bowers, James F. Brien, Kanji Nakatsu, Walter A. Szarek

Journal:

Year:

2005

File:

PDF, 17 KB

2005

8

Heme Oxygenase Inhibition by 1-Aryl-2-(1H-imidazol-1-yl/1H-1,2,4-triazol-1-yl)ethanones and Their Derivatives

Gheorghe Roman, Jason Z. Vlahakis, Dragic Vukomanovic, Kanji Nakatsu, Walter A. Szarek

Journal:

Year:

2010

Language:

english

File:

PDF, 380 KB

english, 2010

9

Determination of Chromium (VI) and (III) by Adsorptive Stripping Voltammetry with Pyrocatechol Violet

Dragic V. Vukomanovic, Gary W. vanloon, Kanji Nakatsu, Dick E. Zoutman

Journal:

Microchemical Journal

Year:

1997

Language:

english

File:

PDF, 104 KB

english, 1997

10

Heme oxygenase inhibition by 2-oxy-substituted 1-(1H-imidazol-1-yl)-4-phenylbutanes: Effect of halogen substitution in the phenyl ring

Gheorghe Roman, John G. Riley, Jason Z. Vlahakis, Robert T. Kinobe, James F. Brien, Kanji Nakatsu, Walter A. Szarek

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 247 KB

english, 2007

11

Synthesis and evaluation of imidazole–dioxolane compounds as selective heme oxygenase inhibitors: Effect of substituents at the 4-position of the dioxolane ring

Jason Z. Vlahakis, Maaike Hum, Mona N. Rahman, Zongchao Jia, Kanji Nakatsu, Walter A. Szarek

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 2.18 MB

english, 2009

12

Synthesis and evaluation of azalanstat analogues as heme oxygenase inhibitors

Jason Z. Vlahakis, Robert T. Kinobe, Raymond J. Bowers, James F. Brien, Kanji Nakatsu, Walter A. Szarek

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 154 KB

english, 2005

13

Heme oxygenase activity and acute and chronic ethanol exposure in the hippocampus, frontal cerebral cortex, and cerebellum of the near-term fetal guinea pig

Michael N. Cook, Gerald S. Marks, Hendrik J. Vreman, Kanji Nakatsu, David K. Stevenson, James F. Brien

Journal:

Year:

1997

Language:

english

File:

PDF, 819 KB

english, 1997

14

Peroxynitrite-mediated inactivation of heme oxygenases

Robert Kinobe, Yanbin Ji, Kanji Nakatsu

Journal:

BMC Pharmacology

Year:

2004

Language:

english

File:

PDF, 553 KB

english, 2004

15

In vitro cytochrome P450 monooxygenase and prostaglandin H-synthase mediated aflatoxin B1biotransformation in guinea pig tissues: Effects of β-naphthoflavone treatment

Ling Liu, Kanji Nakatsu, Thomas E. Massey

Journal:

Archives of Toxicology

Year:

1993

Language:

english

File:

PDF, 702 KB

english, 1993

16

Anti-Plasmodium activity of imidazole–dioxolane compounds

Jason Z. Vlahakis, Robert T. Kinobe, Kanji Nakatsu, Walter A. Szarek, Ian E. Crandall

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 223 KB

english, 2006

17

Heme Oxygenase Inhibition by 2-Oxy-substituted 1-Azolyl-4-phenylbutanes: Effect of Variation of the Azole Moiety. X-Ray Crystal Structure of Human Heme Oxygenase-1 in Complex with 4-Phenyl-1-(1H-1,2,4-triazol-1-yl)-2-butanone

Gheorghe Roman, Mona N. Rahman, Dragic Vukomanovic, Zongchao Jia, Kanji Nakatsu, Walter A. Szarek

Journal:

Chemical Biology & Drug Design

Year:

2010

Language:

english

File:

PDF, 785 KB

english, 2010

18

Selectivity of imidazole–dioxolane compounds for in vitro inhibition of microsomal haem oxygenase isoforms

Robert T Kinobe, Jason Z Vlahakis, Hendrik J Vreman, David K Stevenson, James F Brien, Walter A Szarek, Kanji Nakatsu

Journal:

British Journal of Pharmacology

Year:

2006

Language:

english

File:

PDF, 207 KB

english, 2006

19

Heme Oxygenase Inhibition by α-(1H-Imidazol-1-yl)-ω-phenylalkanes: Effect of Introduction of Heteroatoms in the Alkyl Linker

Dr. Jason Z. Vlahakis, Dr. Carmen Lazar, Dr. Gheorghe Roman, Dr. Dragic Vukomanovic, Prof. Kanji Nakatsu, Prof. Walter A. Szarek

Journal:

Year:

2012

Language:

english

File:

PDF, 236 KB

english, 2012

20

Evaluation of inflammatory diseases of jaw bones with three-dimensional CT imaging Comparison with conventional radiography and high-resolution CT

Kanji Kishi, Kazutoshi Akita, Tsugio Nakatsu, Kiyoyuki Adachi, Masato Uemura, Satoru Ochi, Emiko Saito Arita

Journal:

Year:

1992

Language:

english

File:

PDF, 3.27 MB

english, 1992

21

Clinical and radiographical study of antro-oral fistula

Kanji Kishi, Tsugio Nakatsu, Toru Wakasa, Isao Hasegawa, Masato Uemura, Kazumasa Hazawa, Kenichiro Shimizu, Yuichi Doi

Journal:

Year:

1995

Language:

english

File:

PDF, 834 KB

english, 1995

22

Internal carotid artery aneurysm with prominent calcification: Report of a case

Toru Wakasa, Tsugio Nakatsu, Masato Uemura, Tomokazu Fujiki, Kanji Kishi, Nobuo Satoh, Yoshio Hiraki

Journal:

Year:

1992

Language:

english

File:

PDF, 1.18 MB

english, 1992

23

The application of magnetic resonance imaging in maxillo-facial region: A comparison with CT

Kanji Kishi, Makoto Sato, Yoshie Sugihara, Akihiro Yamada, Hideaki Tanaka, Tsugio Nakatsu, Koichi Hirakawa, Ikuo Joja, Yoshio Hiraki, Kaname Aono

Journal:

Year:

1988

Language:

english

File:

PDF, 1.07 MB

english, 1988

24

Clinico-radiographic evaluation of simple bone cyst accompanied by radiopaque lesions

Kiyoyuki Adachi, Hiroshi Shigehara, Satoru Ochi, Tsugio Nakatsu, Kazutoshi Akita, Kanji Kishi

Journal:

Year:

1993

Language:

english

File:

PDF, 1.57 MB

english, 1993

25

Ontogeny of heme oxygenase activity in the hippocampus, frontal cerebral cortex, and cerebellum of the guinea pig

Michael N. Cook, Gerald S. Marks, Hendrik J. Vreman, Kanji Nakatsu, David K. Stevenson, James F. Brien

Journal:

Developmental Brain Research

Year:

1996

Language:

english

File:

PDF, 568 KB

english, 1996

26

A novel method for detection of nitric oxide binding sites by using a chemiluminescence-headspace gas technique

E.Danielle Beaton, Zhenguo Liu, Brian E. McLaughlin, James F. Brien, Kanji Nakatsu, Gerald S. Marks

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

1993

Language:

english

File:

PDF, 706 KB

english, 1993

27

Determination of in vivo carbon monoxide production in laboratory animals via exhaled air

Ryan A. Dercho, Kanji Nakatsu, Ronald J. Wong, David K. Stevenson, Hendrik J. Vreman

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2006

Language:

english

File:

PDF, 292 KB

english, 2006

28

Rapid, convenient method for screening imidazole-containing compounds for heme oxygenase inhibition

Jason Z. Vlahakis, Mona N. Rahman, Gheorghe Roman, Zongchao Jia, Kanji Nakatsu, Walter A. Szarek

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2011

Language:

english

File:

PDF, 749 KB

english, 2011

29

Carbon monoxide formation in the guinea pig hippocampus: ontogeny and effect of in vitro ethanol exposure

Michael N Cook, Gerald S Marks, Hendrik J Vreman, Brian E McLaughlin, Kanji Nakatsu, David K Stevenson, James F Brien

Journal:

Developmental Brain Research

Year:

1997

Language:

english

File:

PDF, 149 KB

english, 1997

30

Porphyrinogenic xenobiotic-induced N-alkylprotoporphyrin IX formation: a bioassay utilizing chick embryo hepatic ferrochelatase

Jeremy T Gamble, Kanji Nakatsu, Gerald S Marks

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2002

Language:

english

File:

PDF, 147 KB

english, 2002

31

Analysis of nanomolar S-nitrosothiol concentrations in physiological media

Dragic V. Vukomanovic, Aman Hussain, Dick E. Zoutman, Gerald S. Marks, James F. Brien, Kanji Nakatsu

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

1998

Language:

english

File:

PDF, 94 KB

english, 1998

32

Action of coenzyme A on adenine derivative receptors in isolated tissues

Khem Jhamandas, Kanji Nakatsu, John W. Downie, Verna Bartlett, Janet Elliott

Journal:

European Journal of Pharmacology

Year:

1980

Language:

english

File:

PDF, 396 KB

english, 1980

33

Carbon monoxide does not inhibit glyceryl trinitrate biotransformation by or relaxation of aorta

Zhenguo Liu, James F. Brien, Gerald S. Marks, Brian E. McLaughlin, Kanji Nakatsu

Journal:

European Journal of Pharmacology

Year:

1992

Language:

english

File:

PDF, 310 KB

english, 1992

34

Nomenclature of nitrogen oxide-containing molecules: Inappropriate use of the term ‘nitrovasodilators’ for drugs with additional effects

Kanji Nakatsu, Gerald S. Marks, James F. Brien

Journal:

Trends in Pharmacological Sciences

Year:

1995

Language:

english

File:

PDF, 142 KB

english, 1995

35

Nitric oxide formation from glyceryl trinitrate by rabbit aortic strip: detection by rabbit taenia coli concurrent with vasorelaxation

Aman S. Hussain, Margo Poklewska-Koziell, James F. Brien, Gerald S. Marks, Kanji Nakatsu

Journal:

British Journal of Pharmacology

Year:

1994

Language:

english

File:

PDF, 1.49 MB

english, 1994

36

Reversible changes in the stability of phosphofructokinase in rat diaphragms

Kanji Nakatsu, Tag E. Mansour

Journal:

Biochemical and Biophysical Research Communications

Year:

1974

Language:

english

File:

PDF, 367 KB

english, 1974

37

Assembly of an inexpensive physiological recorder

James A. Owen, Nakatsu Kanji

Journal:

Journal of Pharmacological Methods

Year:

1978

Language:

english

File:

PDF, 601 KB

english, 1978

38

A microprocessor-based animal monitoring system

Nakatsu Kanji, James A. Owen

Journal:

Journal of Pharmacological Methods

Year:

1980

Language:

english

File:

PDF, 705 KB

english, 1980

39

Assembly of an inexpensive tail flick analgesia meter

James A. Owen, Brian Milne, Khem Jhamandas, Kanji Nakatsu

Journal:

Journal of Pharmacological Methods

Year:

1981

Language:

english

File:

PDF, 413 KB

english, 1981

40

Determination of disopyramide and mono-N-desisopropyl-disopyramide in serum by gas-liquid chromatography with nitrogen-selective detection

James F. Brien, Kanji Nakatsu, Paul W. Armstrong

Journal:

Journal of Pharmacological Methods

Year:

1983

Language:

english

File:

PDF, 943 KB

english, 1983

41

A facile, reliable method for staining blood vessel endothelium

Kanji Nakatsu, Jeffery H. Kawamoto, James F. Brien, Gerald S. Marks

Journal:

Journal of Pharmacological Methods

Year:

1988

Language:

english

File:

PDF, 798 KB

english, 1988

42

Experiences with the commodore VIC-20

Journal:

Trends in Pharmacological Sciences

Year:

1983

Language:

english

File:

PDF, 480 KB

english, 1983

43

Does carbon monoxide have a physiological function?

Gerald S. Marks, James F. Brien, Kanji Nakatsu, Brian E. McLaughlin

Journal:

Trends in Pharmacological Sciences

Year:

1991

Language:

english

File:

PDF, 483 KB

english, 1991

44

X-ray Crystal Structure of Human Heme Oxygenase-1 in Complex with 1-(Adamantan-1-yl)-2-(1 H -imidazol-1-yl)ethanone: A Common Binding Mode for Imidazole-Based Heme Oxygenase-1 Inhibitors #

Rahman, Mona N., Vlahakis, Jason Z., Szarek, Walter A., Nakatsu, Kanji, Jia, Zongchao

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 1.56 MB

english, 2008

45

Selective inhibition of heme oxygenase-2 activity by analogs of 1-(4-chlorobenzyl)-2-(pyrrolidin-1-ylmethyl)-1H-benzimidazole (clemizole): Exploration of the effects of substituents at the N-1 position

Vlahakis, Jason Z., Vukomanovic, Dragic, Nakatsu, Kanji, Szarek, Walter A.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 385 KB

english, 2013

46

In vitroActivation of heme oxygenase-2 by menadione and its analogs

Vukomanovic, Dragic, Rahman, Mona N, Bilokin, Yaroslav, Golub, Andriy G, Brien, James F, Szarek, Walter A, Jia, Zongchao, Nakatsu, Kanji

Journal:

Medical Gas Research

Year:

2014

Language:

english

File:

PDF, 332 KB

english, 2014

47

Shortening of liquid chromatography columns for reduced retention time

Nakatsu, Kanji., Tasker, R. Andrew R., Bukowskyj, Maria.

Journal:

Analytical Chemistry

Year:

1983

Language:

english

File:

PDF, 193 KB

english, 1983

48

X-ray Crystal Structure of Human Heme Oxygenase-1 with (2 R ,4 S )-2-[2-(4-Chlorophenyl)ethyl]-2-[(1 H -imidazol-1-yl)methyl]-4[((5-trifluoromethylpyridin-2-yl)thio)methyl]-1,3-dioxolane: A Novel, Inducible Binding Mode

Rahman, Mona N., Vlahakis, Jason Z., Vukomanovic, Dragic, Szarek, Walter A., Nakatsu, Kanji, Jia, Zongchao

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 3.24 MB

english, 2009

49

Imidazole−Dioxolane Compounds as Isozyme-Selective Heme Oxygenase Inhibitors

Vlahakis, Jason Z., Kinobe, Robert T., Bowers, Raymond J., Brien, James F., Nakatsu, Kanji, Szarek, Walter A.

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 79 KB

english, 2006

50

Measurement of Endogenous Carbon Monoxide Formation in Biological Systems

Marks, Gerald S., Vreman, Hendrik J., McLaughlin, Brian E., Brien, James F., Nakatsu, Kanji

Journal:

Antioxidants & Redox Signaling

Year:

2002

Language:

english

File:

PDF, 174 KB

english, 2002